| Competition: | 2. Bundesliga (women) |
| Season: | 2015–16 |
| Winners: | MSV Duisburg (North) TSG 1899 Hoffenheim II (South) |
| Promoted: | MSV Duisburg (North) Borussia Mönchengladbach (South) |
| Relegated: | Alemannia Aachen FFV Leipzig ETSV Würzburg Holstein Kiel Blau-Weiß Hohen Neuendorf |
| Matches: | 266 |
| Total Goals: | 952 |
| League Topscorer: | Giustina Ronzetti (23 goals) |
| Biggest Home Win: | BV Cloppenburg 11–2 FFV Leipzig (15 May 2016) |
| Biggest Away Win: | TSG 1899 Hoffenheim II 9–0 1. FC Saarbrücken (8 May 2016) |
| Highest Scoring: | BV Cloppenburg 11–2 FFV Leipzig (15 May 2016) |
| Prevseason: | 2014–15 |
| Nextseason: | 2016–17 |
The 2015–16 season of the 2. Bundesliga (women) was the twelfth season of Germany's second-tier women's football league. This season started on 30 August 2015.[1]
VfL Bochum did not apply for this season's license due to financial problems, thus automatically relegating them back to the Regionalliga.[2] SV Henstedt-Ulzburg was promoted from the Regionalliga Nord and played in the north group.[3] Borussia Mönchengladbach was promoted from the Regionalliga West.[4] TSV Schott Mainz was promoted from the Regionalliga Südwest.[5] Eintracht Wetzlar was promoted from the Regionalliga Süd.[6] Blau-Weiß Hohen Neuendorf was promoted from the Regionalliga Nordost.[7]
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 | Giustina Ronzetti | Herforder SV | 23 |
| 2 | Sofia Nati | MSV Duisburg | 22 |
| 3 |  Agnieszka Winczo | BV Cloppenburg | 17 |
| 4 | Nadja Pfeiffer | Borussia Mönchengladbach | 16 |
| 5 | Alina Witt | SV Henstedt-Ulzburg | 15 |
| 6 | Sarah Grünheid | FSV Gütersloh 2009 | 14 |
| 7 | Stefanie Weichelt | MSV Duisburg | 13 |
| Madeleine Wojtecki | 1. FC Lübars | ||
| Julia Matuschewski | FFC Frankfurt II | ||
| Luisa Scheidel | TSV Crailsheim |