| Date: | 15 November – 23 November |
| Edition: | 10th |
| Surface: | Clay |
| Location: | Montevideo, Uruguay |
| Champs: | Pablo Cuevas |
| Champd: | Martín Cuevas / Pablo Cuevas |
The 2014 Uruguay Open is a professional tennis tournament played on clay courts. It is the tenth edition of the tournament which is part of the 2014 ATP Challenger Tour. It will take place in Montevideo, Uruguay between November 15 and November 23, 2014.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Pablo Cuevas | 35 | 1 | ||
 Spain | Pere Riba | 117 | 2 | |
 Argentina | Facundo Argüello | 150 | 3 | |
| Gonzalo Lama | 207 | 4 | ||
| Nicolás Jarry | 228 | 5 | ||
| Spain | Jordi Samper-Montaña | 244 | 6 | |
| Argentina | Andrés Molteni | 259 | 7 | |
| Argentina | Pedro Cachin | 267 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Manuel Barros Luciano Doria
David Volfson Matías BuchhassSee main article: 2014 Uruguay Open – Singles.
Hugo Dellien, 6–2, 6–4See main article: 2014 Uruguay Open – Doubles.