| Champ: |  Paolo Lorenzi |
| Runner: |  Adrián Menéndez Maceiras |
| Score: | 6–1, 6–3 |
| Type: | men |
| After Name: | San Luis Open Challenger Tour |
See main article: 2014 San Luis Potosí Challenger.
Alessio di Mauro was the defending champion, but lost in the quarterfinals to Víctor Estrella Burgos.
Paolo Lorenzi won the title, defeating Adrián Menéndez Maceiras in the final, 6–1, 6–3.
Alejandro Falla (first round) Paolo Lorenzi (champion)
Víctor Estrella Burgos (semifinals) Adrián Menéndez Maceiras (final)
Agustín Velotti (quarterfinals) Daniel Muñoz de la Nava (second round)
Chase Buchanan (first round) Nicolas Meister (first round)