See main article: 2013 San Luis Open Challenger. Nicholas Monroe and Simon Stadler were the defending champions but they decided to participate in the 2013 Seguros Bolívar Open Pereira instead.
Marin Draganja and Adrián Menéndez-Maceiras defeated Marco Chiudinelli and Peter Gojowczyk 6–4, 6–3 in the final to capture the title.