The women's 4 x 100 metre medley relay at the 2013 IPC Swimming World Championships was held at the Parc Jean Drapeau Aquatic Complex in Montreal from 12–18 August.
| Points | width=200 bgcolor=gold | Gold | width=200 bgcolor=silver | Silver | width=200 bgcolor=CC9966 | Bronze |
| 34 points | Stephanie Millward S9 Claire Cashmore SB8 Stephanie Slater S8 Amy Marren S9 | Nina Ryabova S10 Olesya Vladykina SB8 Irina Grazhdanova S9 Oxana Guseva S7 | Lu Dong S6 Zhang Meng SB9 Jiang Shengnan S8 Lin Ping S9 |