The women's 100 metre breaststroke at the 2013 IPC Swimming World Championships was held at the Parc Jean Drapeau Aquatic Complex in Montreal from 12–18 August.
| Class | width=200 bgcolor=gold | Gold | width=200 bgcolor=silver | Silver | width=200 bgcolor=CC9966 | Bronze |
| SB4 | Sarah Louise Rung | Nataliia Prologaieva | Natalia Shavel | |||
| SB5 | Kirsten Bruhn | Noga Nir-Kistler | Verena Schott | |||
| SB6 | Susana Ribeiro | Viktoriia Savtsova | Charlotte Henshaw | |||
| SB7 | Ulyana Kuznetsova | Lisa den Braber | Oksana Khrul | |||
| SB8 | Olesya Vladykina | Claire Cashmore | Ellen Keane | |||
| SB9 | Sophie Pascoe | Harriet Lee | Khrystyna Yurchenko | |||
| SB11 | Maja Reichard | Nadia Baez | Yana Berezhna | |||
| SB12 | Karolina Pelendritou | Emely Telle | Maryna Stabrovska | |||
| SB13 | Elena Krawzow | Colleen Young | Teigan van Roosmalen | |||
| SB14 | Michelle Alonso Morales | Bethany Firth | Nicole Lough |