The men's 4 x 100 metre freestyle relay at the 2013 IPC Swimming World Championships was held at the Parc Jean Drapeau Aquatic Complex in Montreal from 12–18 August.
| Points | width=200 bgcolor=gold | Gold | width=220 bgcolor=silver | Silver | width=200 bgcolor=CC9966 | Bronze |
| 34 pts[1] | Rowan Crothers S9 Matthew Cowdrey S9 Matthew Levy S7 Brenden Hall S9 | Phelipe Andrews Melo Rodrigues S10 Daniel Dias S5 Ruiter Silva S9 Andre Brasil S10 | Alexander Markelov S8 Konstantin Lisenkov S8 Denis Tarasov S8 Dmitry Grigoryev S10 |