The men's 100 metre butterfly at the 2013 IPC Swimming World Championships was held at the Parc Jean Drapeau Aquatic Complex in Montreal from 12–18 August.
| Class | width=200 bgcolor=gold | Gold | width=200 bgcolor=silver | Silver | width=200 bgcolor=CC9966 | Bronze |
| S8 | Song Maodang | Denis Tarasov | Charles Rozoy | |||
| S9 | Federico Morlacchi | Tamás Sors | Matthew Cowdrey | |||
| S10 | Andre Brasil | Dmitry Grigoryev | David Levecq | |||
| S11 | Oleksandr Mashchenko | Israel Oliver | Keiichi Kimura | |||
| S12 | Roman Makarov | Danylo Chufarov | Anton Stabrovskyy | |||
| S13 | Ihar Boki | Roman Dubovoy | Tim Antalfy |