| Date: | July 22–28 |
| Edition: | 18th (men) / 16th (women) |
| Draw: | 32S / 16D |
| Surface: | Hard |
| Location: | Lexington, Kentucky, United States |
| Prize Money: | $50,000 |
| Champms: |  James Ward |
| Champmd: |  Frank Dancevic / Peter Polansky |
| Champws: |  Shelby Rogers |
| Champwd: |  Nicha Lertpitaksinchai / Peangtarn Plipuech |
| After Name: | Kentucky Bank Tennis Championships |
The 2013 Fifth Third Bank Tennis Championships was a professional tennis tournament played on outdoor hard courts. It was the 18th edition for men and the 16th edition for women of the tournament and was part of the 2013 ITF Women's Circuit and the 2013 ATP Challenger Tour, offering prize money of $50,000 each for the men's and women's events. It took place in Lexington, Kentucky, United States, on July 22–28, 2013.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Ukraine | Illya Marchenko | 118 | 1 | |
 Belgium | Olivier Rochus | 148 | 2 | |
| Belgium | Ruben Bemelmans | 153 | 3 | |
| United States | Alex Kuznetsov | 157 | 4 | |
| United States | Bradley Klahn | 161 | 5 | |
 Australia | James Duckworth | 164 | 6 | |
 Japan | Tatsuma Ito | 174 | 7 | |
 Tunisia | Malek Jaziri | 177 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry by a special exempt:
The following players received entry from the qualifying draw:
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Japan | Misaki Doi | 95 | 1 | |
 Israel | Julia Glushko | 113 | 2 | |
| Japan | Kurumi Nara | 125 | 3 | |
| United States | Shelby Rogers | 154 | 4 | |
| Canada | Stéphanie Dubois | 158 | 5 | |
| United States | Grace Min | 162 | 6 | |
| United States | Irina Falconi | 164 | 7 | |
| Chanel Simmonds | 171 | 8 |
The following players received wildcards into the singles main draw:
Stephanie Kent Jamie Loeb Grace MinThe following players received entry from the qualifying draw:
The following player received entry by a lucky loser spot:
Yana Koroleva Alexandra MuellerSee main article: 2013 Fifth Third Bank Tennis Championships – Men's singles.
James Ward def. James Duckworth 4–6, 6–3, 6–4See main article: 2013 Fifth Third Bank Tennis Championships – Women's singles.
Shelby Rogers def. 
Julie Coin 6–4, 7–6(7–3)See main article: 2013 Fifth Third Bank Tennis Championships – Men's doubles.
Frank Dancevic / Peter Polansky vs. Bradley Klahn / 
Michael Venus 7–5, 6–3See main article: 2013 Fifth Third Bank Tennis Championships – Women's doubles.
Nicha Lertpitaksinchai / Peangtarn Plipuech def. Julia Glushko / Chanel Simmonds 7–6(7–5), 6–3