| Date: | 6–12 May |
| Edition: | 5th |
| Location: | Trnava, Slovakia |
| Champs: |  Barbora Záhlavová-Strýcová |
| Champd: |  Mervana Jugić-Salkić / Renata Voráčová |
| Before Name: | Empire Trnava Cup |
The 2013 Empire Slovak Open was a professional tennis tournament played on outdoor clay courts. It was the fifth edition of the tournament which was part of the 2013 ITF Women's Circuit, offering a total of $75,000 in prize money. It took place in Trnava, Slovakia, on 6–12 May 2013.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Slovakia | Jana Čepelová | 83 | 1 | |
 Italy | Karin Knapp | 90 | 2 | |
 Serbia | Vesna Dolonc | 100 | 3 | |
 Hungary | Melinda Czink | 103 | 4 | |
| Czech Republic | Kristýna Plíšková | 105 | 5 | |
 United States | Alexa Glatch | 116 | 6 | |
 France | Stéphanie Foretz Gacon | 120 | 7 | |
| Eleni Daniilidou | 124 | 8 |
The following players received wildcards into the singles main draw:
Dalma Gálfi Kateřina Siniaková Petra Uberalová Natália VajdováThe following players received entry from the qualifying draw:
The following player received entry into the singles main draw as a lucky loser:
Vivien JuhászováThe following player received entry by a Protected Ranking:
See main article: 2013 Empire Slovak Open – Singles.
Barbora Záhlavová-Strýcová def. Karin Knapp 6–2, 6–4See main article: 2013 Empire Slovak Open – Doubles.
Mervana Jugić-Salkić / Renata Voráčová def. Jana Čepelová / Anna Karolína Schmiedlová 6–1, 6–1