The 2013 Città di Caltanissetta was a professional tennis tournament played on clay courts. It was the 15th edition of the tournament which was part of the 2013 ATP Challenger Tour. It took place in Caltanissetta, Italy between 3 and 9 June 2013.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Slovakia | Martin Kližan | 35 | 1 | |
| Robin Haase | 66 | 2 | ||
 Argentina | Leonardo Mayer | 73 | 3 | |
| Argentina | Guido Pella | 83 | 4 | |
| Thiemo de Bakker | 95 | 5 | ||
| Argentina | Martín Alund | 100 | 6 | |
 Italy | Filippo Volandri | 111 | 7 | |
 Spain | Rubén Ramírez Hidalgo | 123 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry using a protected ranking:
The following players received entry as an alternate into the singles main draw:
The following players received entry from the qualifying draw:
| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Dominik Meffert |  Austria | Philipp Oswald | 249 | 1 | ||
| Thiemo de Bakker | Robin Haase | 254 | 2 | |||
| Jorge Aguilar | Argentina | Federico Delbonis | 336 | 3 | ||
| Argentina | Renzo Olivo | Argentina | Marco Trungelliti | 379 | 4 |
The following pairs received wildcards into the doubles main draw:
Marco Cecchinato / Alessio di Mauro Omar Giacalone / Gianluca Naso Walter Trusendi / Matteo ViolaSee main article: 2013 Città di Caltanissetta – Singles.
Dušan Lajović def. Robin Haase, 7–6(7–4), 6–3See main article: 2013 Città di Caltanissetta – Doubles.
Philipp Oswald def. Alessandro Giannessi / Potito Starace, 6–2, 6–3