The fifty-fifth edition of the Caribbean Series (Serie del Caribe) was played in 2013.
The Series was held from February 1 through February 7, featuring the champion teams of the 2012–2013 season in the Dominican Winter League (Leones del Escogido), Mexican Pacific League (Yaquis de Obregón), Puerto Rican Professional Baseball League (Criollos de Caguas), and Venezuelan Professional Baseball League (Navegantes del Magallanes).
The format consisted of twelve games, in a double round-robin format with each team facing each other twice, while the championship game was played between the two best teams of the round robin. All of the games were played at Estadio Sonora in Hermosillo, Mexico.
| Country | Club | W | L | W/L % | Managers | |
| 5 | 2 | .833 | Audo Vicente | |||
| Mexico (*) | 3 | 3 | .500 | Eddy Díaz | ||
| 2 | 4 | .333 | Pedro López | |||
| 2 | 4 | .333 | Luis Sojo | |||
| ||||||
| Player | Statistic | ||||
| Batting | |||||
| Doug Clark (MEX) | .412 | ||||
| Jordany Valdespin (DOM) | 7 | ||||
| Doug Clark (MEX) | 11 | ||||
| Marlon Byrd (MEX) | 4 | ||||
| Alfredo Amézaga (MEX) Renny Osuna (VEN) | 1 | ||||
| Mario Lisson (VEN) Francisco Peña (DOM) Miguel Tejada (DOM) | Home runs | 2 | |||
| Ricardo Nanita (DOM) | 7 | ||||
| Hanley Ramírez (DOM) | Stolen bases | 4 | |||
| Pitching | |||||
| Luis Mendoza (MEX) | 2 | ||||
| Angel Castro (DOM) | Strikeouts | 14 | |||
| Luis Mendoza (MEX) | 0.00 | ||||
| Angel Castro (DOM) | |||||
| Saúl Rivera (DOM) | 2 | ||||
| Name | Position | ||||
| Francisco Peña (DOM) | Catcher | ||||
| Donell Linares (DOM) | First baseman | ||||
| José Ramírez (DOM) | Second baseman | ||||
| Mario Lisson (VEN) | Third baseman | ||||
| Miguel Tejada (DOM) | Shortstop | ||||
| Marlon Byrd (MEX) | Outfielder | ||||
| Doug Clark (MEX) | Outfielder | ||||
| Ricardo Nanita (DOM) | Outfielder | ||||
| Bárbaro Cañizares (MEX) | Designated hitter | ||||
| Luis Mendoza (MEX) | Right-handed starting pitcher | ||||
| Efraim Nieves (PUR) | Left-handed starting pitcher | ||||
| David Reyes (MEX) | Relief pitcher | ||||
| Saúl Rivera (VEN) | Closer | ||||
| Awards | |||||
| Luis Mendoza (MEX) | Most Valuable Player | ||||
| Audo Vicente (DOM) | |||||
* Tejada extended an all-time home run record (15) in the Series he already held.