| Champ: |  Andy Murray |
| Runner: | Grigor Dimitrov |
| Score: | 7–6(7–0), 6–4 |
| Draw: | 28 (4 / 3) |
| Seeds: | 8 |
| After Name: | Brisbane International – Men's singles |
| Before Name: | Brisbane International – Men's singles |
See main article: 2013 Brisbane International. Andy Murray was the defending champion, and successfully defended his title, defeating Grigor Dimitrov in the final, 7–6(7–0), 6–4.
The top four seeds received a bye into the second round.
