See main article: 2013 Australian Open. Bethanie Mattek-Sands and Horia Tecău were the defending champions, but lost in the first round to Lucie Hradecká and František Čermák.
Jarmila Gajdošová and Matthew Ebden won their first mixed doubles title, defeating Hradecká and František Čermák in the final, 6–3, 7–5. This would be Gajdošová's only Grand Slam title before her retirement in 2017.