| Score: | 6–1, 5–7, 6–2 |
| Draw: | 128 (12 / 7) |
| Seeds: | 32 |
| Before Name: | Wimbledon Championships – Women's singles |
| After Name: | Wimbledon Championships – Women's singles |
See main article: 2012 Wimbledon Championships. Serena Williams defeated Agnieszka Radwańska in the final, 6–1, 5–7, 6–2 to win the ladies' singles tennis title at the 2012 Wimbledon Championships.[1] It was her fifth Wimbledon singles title (tying her for the third-most Wimbledon singles titles in the Open Era with her sister Venus) and her 14th major singles title overall. Radwańska became the first Pole to reach a major singles final since Jadwiga Jędrzejowska in 1939, and the first in the Open Era.
Petra Kvitová was the defending champion, but lost in the quarterfinals to Williams. With the loss of Maria Sharapova in the fourth round, a first time finalist was guaranteed at the top half of the draw.
Yaroslava Shvedova became the first player in the Open Era to win a 'golden set' at Wimbledon, winning the first set of her 6–0, 6–4 victory over the reigning French Open runner-up and 10th seed Sara Errani in the third round without dropping a single point.[2]
Sabine Lisicki defeated the reigning French Open champion (world No. 1 Sharapova) en route to the Wimbledon quarterfinals for the third straight time. She previously defeated Li Na in 2011 and Svetlana Kuznetsova in 2009, and missed the 2010 Championships due to injury.
Victoria Azarenka regained the world No. 1 ranking by reaching the quarterfinals after Sharapova failed to reach the final. Four of the top five seeds were in contention for the top ranking.
See also: 1 and 1. 
Maria Sharapova (fourth round)
See also: 2 and 8. 
Victoria Azarenka (semifinals)
See also: 3 and 3. 
Agnieszka Radwańska (final)
See also: 4 and 6. 
Petra Kvitová (quarterfinals)
See also: 5 and 4. 
Samantha Stosur (second round)
See also: 6 and 5. 
Serena Williams (champion)
See also: 7 and 7. Caroline Wozniacki (first round)
See also: 8 and 2. Angelique Kerber (semifinals)
See also: 9 and 7. 
Marion Bartoli (second round)
See also: 10 and 5. 
Sara Errani (third round)
See also: 11 and 4. 
Li Na (second round)
See also: 12 and 2. Vera Zvonareva (third round, retired)
See also: 13 and 6. 
Dominika Cibulková (first round)
See also: 14 and 8. 
Ana Ivanovic (fourth round)
See also: 15 and 1. Sabine Lisicki (quarterfinals)
See also: 16 and 3. Flavia Pennetta (first round)
See also: 17 and 4. Maria Kirilenko (quarterfinals)
See also: 18 and 2. Jelena Janković (first round)
See also: 19 and 5. Lucie Šafářová (first round)
See also: 20 and 3. Nadia Petrova (third round)
See also: 21 and 7. Roberta Vinci (fourth round)
See also: 22 and 8. Julia Görges (third round)
See also: 23 and 1. Petra Cetkovská (second round)
See also: 24 and 6. Francesca Schiavone (fourth round)
See also: 25 and 5. Zheng Jie (third round)
See also: 26 and 8. 
Anabel Medina Garrigues (second round)
See also: 27 and 3. Daniela Hantuchová (first round)
See also: 28 and 2. Christina McHale (third round)
See also: 29 and 1. Monica Niculescu (first round)
See also: 30 and 4. Peng Shuai (fourth round)
See also: 31 and 6. Anastasia Pavlyuchenkova (second round)
See also: 32 and 7. Svetlana Kuznetsova (first round)
See main article: 2012 Wimbledon Championships – Women's singles qualifying.
| Category | S. Williams | Radwańska | |
|---|---|---|---|
| 1st serve % | 45/80 (56%) | 72/99 (73%) | |
| 1st serve points won | 37 of 45 = 82% | 44 of 72 = 61% | |
| 2nd serve points won | 17 of 35 = 49% | 10 of 27 = 37% | |
| Total service points won | 54 of 80 = 67.50% | 54 of 99 = 54.55% | |
| Aces | 17 | 2 | |
| Double faults | 4 | 5 | |
| Winners | 58 | 13 | |
| Unforced errors | 36 | 14 | |
| Net points won | 21 of 30 = 70% | 10 of 17 = 59% | |
| Break points converted | 5 of 15 = 33% | 2 of 2 = 100% | |
| Return points won | 45 of 99 = 45% | 26 of 80 = 33% | |
| Total points won | bgcolor=98FB989 | 99 | 80 |
| Source | |||