The 2012 Visit Panamá Cup was a professional tennis tournament played on clay courts. It was the first edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Panama City, Panama between 2 and 8 July 2012.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Michael Russell | 112 | 1 | ||
 Brazil | Rogério Dutra da Silva | 114 | 2 | |
 Canada | Peter Polansky | 179 | 3 | |
 Colombia | Carlos Salamanca | 189 | 4 | |
| Colombia | Alejandro González | 226 | 5 | |
 Dominican Republic | Víctor Estrella | 228 | 6 | |
| Colombia | Eduardo Struvay | 273 | 7 | |
 Ecuador | Júlio César Campozano | 331 | 8 |
The following players received wildcards into the singles main draw:
Walner Espinoza
William KarlbergThe following players received entry from the qualifying draw:
Phillip Simmonds Felipe Escobar
Christian Ignacio BenedettiSee main article: 2012 Visit Panamá Cup – Singles.
Rogério Dutra da Silva def. Peter Polansky, 6–3, 6–0See main article: 2012 Visit Panamá Cup – Doubles.
Júlio César Campozano / Alejandro González def. Daniel Kosakowski / Peter Polansky, 6–4, 7–5