See main article: 2012 Uruguay Open. Nikola Ćirić and Goran Tošić were the defending champions but Ćirić decided not to participate.
Tošić played alongside Boris Pašanski.
Nikola Mektić and Antonio Veić defeated Blaž Kavčič and Franco Škugor 6–3, 5–7, [10–7] in the final to win the title.