| Champ: |  Samantha Crawford |
| Runner: |  Anett Kontaveit |
| Score: | 7–5, 6–3 |
See main article: 2012 US Open (tennis).
Grace Min was the defending champion, having won the event in 2011, but did not compete.
Wildcard Samantha Crawford defeated twelfth seed Anett Kontaveit in the final 7–5, 6–3, to win her first junior grand slam title.