| Champ: |  Roberta Vinci |
| Runner: |  Jelena Janković |
| Score: | 7–5, 6–3 |
| Type: | singles doubles |
| After Year: | no |
See main article: 2012 Texas Tennis Open. Sabine Lisicki was the defending champion, but withdrew because of a left abdominal sprain. Roberta Vinci defeated Jelena Janković 7–5, 6–3 in the final to win the tournament.
