| Date: | 8–14 October |
| Edition: | 5th |
| Surface: | Hard |
| Location: | Tashkent, Uzbekistan |
| Champs: |  Uladzimir Ignatik |
| Champd: | Andre Begemann / Martin Emmrich |
The 2012 Tashkent Challenger was a professional tennis tournament played on hard courts. It was the fifth edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Tashkent, Uzbekistan between 8 and 14 October 2012.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Slovakia | Lukáš Lacko | 65 | 1 | |
 Italy | Flavio Cipolla | 78 | 2 | |
 Israel | Dudi Sela | 98 | 3 | |
 Tunisia | Malek Jaziri | 112 | 4 | |
| Ivan Dodig | 113 | 5 | ||
 Canada | Vasek Pospisil | 115 | 6 | |
 Russian Federation | Dmitry Tursunov | 117 | 7 | |
| Slovakia | Karol Beck | 128 | 8 |
The following players received wildcards into the singles main draw:
Farrukh Dustov Sarvar Ikramov Sergey Shipilov Nigmat ShofayzievThe following players received entry from the qualifying draw:
See main article: 2012 Tashkent Challenger – Singles.
Uladzimir Ignatik def. Lukáš Lacko, 6–3, 7–6(7–3)See main article: 2012 Tashkent Challenger – Doubles.
Rameez Junaid / Frank Moser, 6–7(2–7), 7–6(7–2), [10–8]
