The 2012 SAP Open was a tennis tournament played on indoor hard courts. It was the 124th edition of the SAP Open, and was part of the ATP World Tour 250 series of the 2012 ATP World Tour. It took place at the HP Pavilion in San Jose, California, United States, from February 13 through February 19, 2012. Third-seeded Milos Raonic won the singles title.
| Country | Player | Ranking1 | Seeding | |
|---|---|---|---|---|
 France | Gaël Monfils | 13 | 1 | |
 United States | Andy Roddick | 19 | 2 | |
 Canada | Milos Raonic | 29 | 3 | |
| Radek Štěpánek | 30 | 4 | ||
| Kevin Anderson | 37 | 5 | ||
| France | Julien Benneteau | 35 | 6 | |
| United States | Donald Young | 39 | 7 | |
| Olivier Rochus | 50 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
Gaël Monfils (knee injury)| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
 Mexico | Santiago González | Christopher Kas | 42 | 1 | ||
| Scott Lipsky | Rajeev Ram | 66 | 2 | |||
 Australia | Paul Hanley | Jamie Murray | 84 | 3 | ||
| Mark Knowles | Xavier Malisse | 92 | 4 |
The following pairs received wildcards into the doubles main draw:
See main article: 2012 SAP Open – Singles. Milos Raonic defeated 
Denis Istomin, 7–6(7–3), 6–2
See main article: 2012 SAP Open – Doubles. Mark Knowles / 
Xavier Malisse defeated Kevin Anderson / Frank Moser, 6–4, 1–6, [10–5]