The 2012 Rio Quente Resorts Tennis Classic was a professional tennis tournament played on hard courts. It was the first edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Rio Quente, Brazil between 7 and 12 May 2012.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Paul Capdeville | 114 | 1 | ||
 Brazil | Ricardo Mello | 141 | 2 | |
| Brazil | Júlio Silva | 147 | 3 | |
| Brazil | Thiago Alves | 153 | 4 | |
 Czech Republic | Ivo Minář | 181 | 5 | |
| Marcel Felder | 247 | 6 | ||
| Brazil | Ricardo Hocevar | 255 | 7 | |
 Argentina | Nicolás Pastor | 274 | 8 |
The following players received wildcards into the singles main draw:
Tiago Fernandes Pedro Guimares Bruno Sant'anna Marcelo Tebet FilhoThe following players received entry from the qualifying draw:
Andrea Collarini Eduardo Dischinger Augusto Laranja Ivo MinářSee main article: 2012 Rio Quente Resorts Tennis Classic – Singles.
Guilherme Clezar def. Paul Capdeville, 7–6(7–4), 6–3See main article: 2012 Rio Quente Resorts Tennis Classic – Doubles.
Guido Andreozzi / Marcel Felder def. Thiago Alves / Augusto Laranja, 6–3, 6–3