The 2012 Party Rock Open was a professional tennis tournament played on hard courts. It is the fourth edition of the tournament which is part of the 2012 ITF Women's Circuit. It took place in Las Vegas, United States on September 24–30, 2012.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Romania | Edina Gallovits-Hall | 114 | 1 | |
| Lauren Davis | 115 | 2 | ||
| Michelle Larcher de Brito | 120 | 3 | ||
 Australia | Anastasia Rodionova | 130 | 4 | |
| Irina Falconi | 150 | 5 | ||
| Alison Riske | 151 | 6 | ||
| Mallory Burdette | 160 | 7 | ||
 Canada | Heidi El Tabakh | 161 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
See main article: 2012 Party Rock Open – Singles.
Lauren Davis def. Shelby Rogers, 6–7(5–7), 6–2, 6–2See main article: 2012 Party Rock Open – Doubles.
Anastasia Rodionova / 
Arina Rodionova def. Elena Bovina / Edina Gallovits-Hall, 6–2, 2–6, [10–6]