The 2012 PTT Thailand Open was a men's tennis tournament played on indoor hard courts. It was the 10th edition of the Thailand Open, and part of the ATP World Tour 250 Series of the 2012 ATP World Tour. It took place at the Impact Arena in Bangkok, Thailand, from 22 September through 30 September 2012. Richard Gasquet won the singles title.
| Country | Player | Rank* | Seed | |
|---|---|---|---|---|
| Janko Tipsarević | 9 | 1 | ||
| Richard Gasquet | 14 | 2 | ||
| Milos Raonic | 15 | 3 | ||
| Gilles Simon | 20 | 4 | ||
| Fernando Verdasco | 23 | 5 | ||
| Viktor Troicki | 31 | 6 | ||
| Jarkko Nieminen | 39 | 7 | ||
| Bernard Tomic | 42 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Yūichi Sugita (right ankle injury)| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
 India | Leander Paes |  Romania | Horia Tecău | 11 | 1 | |
| Santiago González | Scott Lipsky | 56 | 2 | |||
 Spain | David Marrero | Fernando Verdasco | 58 | 3 | ||
| Eric Butorac | Paul Hanley | 74 | 4 |
The following pairs received wildcards into the doubles main draw:
See main article: 2012 PTT Thailand Open – Singles. 
Richard Gasquet defeated Gilles Simon, 6–2, 6–1
See main article: 2012 PTT Thailand Open – Doubles. Lu Yen-hsun / 
Danai Udomchoke defeated 
Eric Butorac / 
Paul Hanley, 6–3, 6–4
