| Champ: |  Jo-Wilfried Tsonga |
| Runner: |  Andreas Seppi |
| Score: | 6–1, 6–2 |
| Draw: | 28 |
| Seeds: | 8 |
| Type: | singles doubles |
See main article: 2012 Moselle Open. Jo-Wilfried Tsonga successfully defended his title, defeating Andreas Seppi in the final, 6–1, 6–2.
The top four seeds receive a bye into the second round.