| Champ: |  Igor Kunitsyn |
| Runner: |  Dzmitry Zhyrmont |
| Score: | 7–6(12–10), 6–2 |
| Type: | singles doubles |
See main article: 2012 Karshi Challenger. Denis Istomin was the defending champion, but chose not to compete.
Igor Kunitsyn won the title, defeating Dzmitry Zhyrmont 7–6(12–10), 6–2 in the final.