| Runner: |  Łukasz Kubot Janko Tipsarević |
| Score: | 6–3, 6–2 |
See main article: 2012 Italian Open (tennis). John Isner and Sam Querrey were the defending champions but lost in the first round to Jürgen Melzer and Philipp Petzschner.
Marcel Granollers and Marc López won the title defeating Łukasz Kubot and Janko Tipsarević 6–3, 6–2 in the final.
All seeds receive a bye into the second round.