| Date: | 28 July – 5 August |
| Edition: | 4th |
| Surface: | Clay (outdoor) |
| Location: | Trnava, Slovakia |
| Champs: | Anastasija Sevastova |
| Champd: |  Elena Bogdan /  Renata Voráčová |
| After Name: | Empire Slovak Open |
The 2012 Empire Trnava Cup was a professional tennis tournament played on outdoor clay courts. It was the fourth edition of the tournament which was part of the 2012 ITF Women's Circuit. It took place in Trnava, Slovakia, on 28 July – 5 August 2012.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Dinah Pfizenmaier | 128 | 1 | ||
 Russian Federation | Valeria Savinykh | 133 | 2 | |
 Italy | Nastassja Burnett | 137 | 3 | |
 Austria | Yvonne Meusburger | 139 | 4 | |
 Ukraine | Yuliya Beygelzimer | 160 | 5 | |
| Bibiane Schoofs | 161 | 6 | ||
| Anastasija Sevastova | 166 | 7 | ||
| Elitsa Kostova | 167 | 8 |
The following players received wildcards into the singles main draw:
Gabriela Pantůčková
Nikola VajdováThe following players received entry from the qualifying draw:
Martina Borecká Iris Khanna
Hilda MelanderSee main article: 2012 Empire Trnava Cup – Singles.
See main article: 2012 Empire Trnava Cup – Doubles.
Elena Bogdan / Renata Voráčová def. 
Marta Domachowska / Sandra Klemenschits 7–6(7–2), 6–4