| Date: | April 16–22 |
| Edition: | 12th |
| Surface: | Clay |
| Location: | Dothan, Alabama, United States |
| Champs: |  Camila Giorgi |
| Champd: |  Eugenie Bouchard /  Jessica Pegula |
The 2012 Dothan Pro Tennis Classic was a professional tennis tournament played on clay courts. It was the twelfth edition of the tournament which was part of the 2012 ITF Women's Circuit, offering a total of $50,000 in prize money. It took place in Dothan, Alabama, United States, on April 16–22, 2012.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Canada | Stéphanie Dubois | 92 | 1 | |
 Romania | Edina Gallovits-Hall | 96 | 2 | |
| United States | Irina Falconi | 104 | 3 | |
| Mirjana Lučić-Baroni | 108 | 4 | ||
 Russian Federation | Alla Kudryavtseva | 117 | 5 | |
 Japan | Misaki Doi | 122 | 6 | |
| United States | Alison Riske | 124 | 7 | |
| Japan | Erika Sema | 134 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entry by a junior exempt:
See main article: 2012 Dothan Pro Tennis Classic – Singles.
Camila Giorgi def. Edina Gallovits-Hall, 6–2, 4–6, 6–4See main article: 2012 Dothan Pro Tennis Classic – Doubles.
Eugenie Bouchard / Jessica Pegula def. Sharon Fichman / Marie-Ève Pelletier, 6–4, 4–6, [10–5]