The 2012 Copa Claro was a men's tennis tournament played on outdoor clay courts. It was the 15th edition of the Copa Claro, and it was part of the ATP World Tour 250 series of the 2012 ATP World Tour. It took place in Buenos Aires, Argentina, from February 18 through February 26, 2012. David Ferrer won the singles title.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Spain | David Ferrer | 5 | 1 | |
| Spain | Nicolás Almagro | 11 | 2 | |
 France | Gilles Simon | 12 | 3 | |
 Japan | Kei Nishikori | 18 | 4 | |
 Argentina | Juan Mónaco | 22 | 5 | |
| Stanislas Wawrinka | 26 | 6 | ||
| Spain | Fernando Verdasco | 27 | 7 | |
| Argentina | Juan Ignacio Chela | 28 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
The following player received entry as lucky loser:
Thomaz Bellucci (ankle injury) Albert Montañés (back injury)
Filippo Volandri (right ankle injury)| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Italy | Daniele Bracciali | Italy | Potito Starace | 89 | 1 | |
| Michal Mertiňák | André Sá | 115 | 2 | |||
| Spain | Pablo Andújar | Carlos Berlocq | 162 | 3 | ||
| Spain | Pere Riba | João Souza | 270 | 4 |
The following pairs received wildcards into the doubles main draw:
The following pair received entry as alternates:
Albert Montañés (back injury)See main article: 2012 Copa Claro – Singles. David Ferrer defeated Nicolás Almagro 4–6, 6–3, 6–2
See main article: 2012 Copa Claro – Doubles. David Marrero / Fernando Verdasco defeated 
Michal Mertiňák / André Sá 6–4, 6–4
