| Year: | 2012 |
| Team: | Charleston Southern Buccaneers |
| Sport: | football |
| Conference: | Big South Conference |
| Short Conf: | Big South |
| Record: | 5–6 |
| Conf Record: | 3–3 |
| Head Coach: | Jay Mills |
| Hc Year: | 10th |
| Off Coach: | Patrick Nix |
| Oc Year: | 2nd |
| Def Coach: | Shawn Quinn |
| Dc Year: | 1st |
| Stadium: | Buccaneer Field |
The 2012 Charleston Southern Buccaneers football team represented Charleston Southern University as a member of the Big South Conference during the 2012 NCAA Division I FCS football season. Led by Jay Mills in his tenth and final season as head coach, the Buccaneers compiled an overall record of 5–6 with a mark of 3–3 in conference play, placing fourth in the Big South. Charleston Southern played home games at Buccaneer Field in Charleston, South Carolina.