The 2012 Busan Open Challenger Tennis was a professional tennis tournament played on hard courts. It was the tenth edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Busan, South Korea between 7 and 13 May 2012.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Yen-Hsun Lu | 57 | 1 | ||
 Japan | Tatsuma Ito | 80 | 2 | |
| Marco Chiudinelli | 135 | 3 | ||
| Rik de Voest | 139 | 4 | ||
| Izak van der Merwe | 158 | 5 | ||
 Thailand | Danai Udomchoke | 173 | 6 | |
| Yang Tsung-hua | 175 | 7 | ||
 Israel | Amir Weintraub | 186 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Kim Cheong-eui
Michael McClune Kento TakeuchiSee main article: 2012 Busan Open Challenger Tennis – Singles.
Tatsuma Ito def. 
John Millman, 6–4, 6–3See main article: 2012 Busan Open Challenger Tennis – Doubles.
Yuki Bhambri / Divij Sharan def. Hsieh Cheng-peng / Lee Hsin-han, 1–6, 6–1, [10–5]