The 2012 Aberto de Florianópolis was a professional tennis tournament played on hard courts. It was the fifth edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Florianópolis, Brazil between February 27 and March 4, 2012.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 France | Éric Prodon | 103 | 1 | |
| Wayne Odesnik | 107 | 2 | ||
 Brazil | Rogério Dutra da Silva | 109 | 3 | |
 Slovenia | Blaž Kavčič | 110 | 4 | |
 Argentina | Diego Junqueira | 112 | 5 | |
| Brazil | Ricardo Mello | 120 | 6 | |
 Spain | Rubén Ramírez Hidalgo | 123 | 7 | |
 Italy | Simone Bolelli | 134 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
See main article: 2012 Aberto de Florianópolis – Singles. Simone Bolelli def. Blaž Kavčič, 6–3, 6–4
See main article: 2012 Aberto de Florianópolis – Doubles. Blaž Kavčič / Antonio Veić def. Javier Martí / Leonardo Tavares, 6–3, 6–3