The 2012–13 season of the Bolivian Liga Nacional B, the second category of Bolivian football, was played by 15 teams.
| width=150px | Club | width=300px | Classification |
|---|---|---|---|
| Ciclón | 2012 Copa Bolivia 2nd place | ||
| Enrique Happ | 2012 Copa Bolivia Champion | ||
| Flamengo | Chuquisaca Championship | ||
| García Agreda | Tarija Championship | ||
| Guabirá | Relegated from 2011–12 Liga Nacional A | ||
| Municipalidad | Champions of Torneo Nacional Provincial | ||
| Oruro Royal | Oruro Championship | ||
| Real Mamoré | Relegated from 2011–12 Liga Nacional A | ||
| Sport Boys | 2012 Copa Bolivia 3rd place | ||
| Unión Maestranza | La Paz Championship | ||
| Universidad de Santa Cruz | Santa Cruz Championship | ||
| Universitario (Beni) | Beni Championship | ||
| Universitario (San Simón) | Cochabamba Championship | ||
| Vaca Díez | Pando Championship | ||
| Wilstermann Cooperativas | Potosi Championship | ||