The 2011 UniCredit Czech Open was a professional tennis tournament played on outdoor red clay courts. It was part of the 2011 ATP Challenger Tour. It took place in Prostějov, Czech Republic between 30 May and 5 June 2011.
| Nationality | Player | Ranking* | Seeding | |
|---|---|---|---|---|
| Mikhail Youzhny | 13 | 1 | ||
| Tommy Robredo | 31 | 2 | ||
| Andreas Seppi | 51 | 3 | ||
| Daniel Gimeno Traver | 55 | 4 | ||
| Lu Yen-hsun | 56 | 5 | ||
| Radek Štěpánek | 57 | 6 | ||
| Carlos Berlocq | 69 | 7 | ||
| Filippo Volandri | 73 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
See main article: 2011 UniCredit Czech Open – Singles. 
Yuri Schukin def. Flavio Cipolla, 6–4, 4–6, 6–0
See main article: 2011 UniCredit Czech Open – Doubles. 
Sergei Bubka / 
Adrián Menéndez def. David Marrero / Rubén Ramírez Hidalgo, 7–5, 6–2