The 2011 Strabag Prague Open was a professional tennis tournament played on clay courts. It was the 18th edition of the men's tournament which was part of the 2011 ATP Challenger Tour and the 10th edition of the women's tournament, part of 2011 ITF Women's Circuit. It was part of the WTA Tour in the previous year, but was degraded to ITF event this year. It took place in Prague, Czech Republic between 2 and 8 May 2011.
The tournament included tennis exhibition involving Karolína Plíšková, Kristýna Plíšková and Martina Hingis and Daja Bedanova.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 France | Jérémy Chardy | 53 | 1 | |
| Grigor Dimitrov | 69 | 2 | ||
| France | Julien Benneteau | 83 | 3 | |
| Matthias Bachinger | 96 | 4 | ||
 Czech Republic | Jan Hájek | 98 | 5 | |
| France | Florent Serra | 100 | 6 | |
| Rui Machado | 102 | 7 | ||
| Alex Bogomolov Jr. | 104 | 8 |
The following players received wildcards into the singles main draw:
Jan Blecha
Tiago Fernandes Jiří VeselýThe following players received entry as a special exempt into the singles main draw:
The following players received entry from the qualifying draw:
Aliaksandr Bury Nicolas Devilder
James Lemke| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Czech Republic | Lucie Hradecká | 66 | 1 | |
 Italy | Romina Oprandi | 92 | 2 | |
| Czech Republic | Andrea Hlaváčková | 94 | 3 | |
 Austria | Patricia Mayr-Achleitner | 97 | 4 | |
| Austria | Yvonne Meusburger | 119 | 5 | |
 Japan | Misaki Doi | 124 | 6 | |
 Ukraine | Lesia Tsurenko | 128 | 7 | |
| Sabine Lisicki | 132 | 8 |
The following players received wildcards into the singles main draw:
Tereza Hejlová Karolína Plíšková Krystina PlíškováThe following players received entry from the qualifying draw:
The following players received entry as a lucky loser:
See main article: 2011 Strabag Prague Open – Men's singles. Lukáš Rosol defeated 
Alex Bogomolov Jr., 7–6(7–1), 5–2 retired
See main article: 2011 Strabag Prague Open – Women's singles. Lucie Hradecká defeated 
Paula Ormaechea, 4–6, 6–3, 6–2
See main article: 2011 Strabag Prague Open – Men's doubles. František Čermák / Lukáš Rosol defeated Christopher Kas / Alexander Peya, 6–3, 6–4
See main article: 2011 Strabag Prague Open – Women's doubles. Darya Kustova / 
Arina Rodionova defeated Olga Savchuk / Lesia Tsurenko, 2–6, 6–1, [10–7]
