The 2011 Seguros Bolívar Open Cali was a professional tennis tournament played on clay courts. It was the fourth edition of the tournament which was part of the 2011 ATP Challenger Tour. It took place in Cali, Colombia between 19 and 25 September 2011.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Argentina | Horacio Zeballos | 109 | 1 | |
 Colombia | Alejandro Falla | 114 | 2 | |
| Argentina | Facundo Bagnis | 169 | 3 | |
| Colombia | Carlos Salamanca | 172 | 4 | |
 Dominican Republic | Víctor Estrella | 229 | 5 | |
| Colombia | Juan Sebastián Cabal | 237 | 6 | |
| Argentina | Eduardo Schwank | 242 | 7 | |
| Colombia | Alejandro González | 257 | 8 |
The following players received wildcards into the singles main draw:
Nicolás Barrientos Felipe Escobar Alejandro Falla Horacio ZeballosThe following players received entry from the qualifying draw:
Juan Sebastián Gómez Juan Pablo Ortiz Michael Quintero Sebastián SerranoThe following players received entry as a lucky loser into the singles main draw:
Steffen ZornosaSee main article: 2011 Seguros Bolívar Open Cali – Singles. Alejandro Falla def. Eduardo Schwank, 6–4, 6–3
See main article: 2011 Seguros Bolívar Open Cali – Doubles. Juan Sebastián Cabal / Robert Farah def. Facundo Bagnis / Eduardo Schwank, 7–5, 6–2