| Date: | February 13–20 |
| Edition: | 36th (Men) / 26th (Women) |
| Category: | ATP World Tour 500 |
| Champms: |  Andy Roddick |
| Champws: |  Magdaléna Rybáriková |
| Champmd: |  Max Mirnyi /  Daniel Nestor |
| Champwd: | Olga Govortsova /  Alla Kudryavtseva |
The 2011 Regions Morgan Keegan Championships and the Cellular South Cup was an ATP World Tour and WTA Tour event held at the hardcourts of the Racquet Club of Memphis in Memphis, Tennessee in the United States. It was the 35th edition of the Regions Morgan Keegan Championships and the 26th edition of the Cellular South Cup. The Regions Morgan Keegan Championships was part of the ATP World Tour 500 series on the 2011 ATP World Tour, and the Cellular South Cup was an International-level tournament on the 2011 WTA Tour. The event took place from 13 February through 20 to February, 2011.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Czech Republic | 56 | 1 | ||
 Sweden | Sofia Arvidsson | 60 | 2 | |
| United States | Melanie Oudin | 61 | 3 | |
| Russian Federation | Alla Kudryavtseva | 71 | 4 | |
| Belarus | Olga Govortsova | 73 | 5 | |
| Canada | Rebecca Marino | 84 | 6 | |
| Czech Republic | Renata Voráčová | 85 | 7 | |
| United States | Vania King | 86 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
The following player received the Lucky loser spot:
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| United States | Andy Roddick | 8 | 1 | |
 Spain | Fernando Verdasco | 9 | 2 | |
 France | ||||
| United States | Mardy Fish | 16 | 4 | |
| United States | Sam Querrey | 17 | 5 | |
| United States | John Isner | 23 | 6 | |
| Lu Yen-hsun | 38 | 7 | ||
| Kevin Anderson | 40 | 8 | ||
 Belgium | Xavier Malisse | 45 | 9 |
The following players received wildcards into the main draw:
The following player received entry as an alternate:
The following players received entry from the qualifying draw:
See main article: 2011 Regions Morgan Keegan Championships – Singles qualifying.
See main article: 2011 Regions Morgan Keegan Championships – Singles. Andy Roddick defeated Milos Raonic, 7–6(8–6), 6–7(11–13), 7–5
See main article: 2011 Cellular South Cup – Singles. Magdaléna Rybáriková defeated Rebecca Marino, 6–2, ret.
See main article: 2011 Regions Morgan Keegan Championships – Doubles. Max Mirnyi / Daniel Nestor defeated Eric Butorac / Jean-Julien Rojer, 6–2, 6–7(6–8), [10–3]
See main article: 2011 Cellular South Cup – Doubles. Olga Govortsova / Alla Kudryavtseva defeated Andrea Hlaváčková / Lucie Hradecká, 6–3, 4–6, [10–8]
