See main article: 2011 Kremlin Cup. Victoria Azarenka was the defending champion, but chose to compete at the BGL Luxembourg Open instead.
Dominika Cibulková won her first WTA tour title, defeating Kaia Kanepi in the final 3–6, 7–6(7–1), 7–5.
The top four seeds receive a bye into the second round.
See main article: 2011 Kremlin Cup – Women's singles qualifying.