The 2011 Delray Beach International Tennis Championships was a professional tennis tournament played on hard courts. It was the 19th edition of the tournament which was part of the World Tour 250 series of the 2011 ATP World Tour. It took place in Delray Beach, United States between 21 and 27 February 2011. Unseeded Juan Martín del Potro, who entered on a Special Exempt, won the singles title.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Andy Roddick | 8 | 1 | ||
| Mardy Fish | 17 | 2 | ||
| Sam Querrey | 18 | 3 | ||
| John Isner | 24 | 4 | ||
| Kevin Anderson | 40 | 5 | ||
 Serbia | Janko Tipsarević | 51 | 6 | |
| Benjamin Becker | 57 | 7 | ||
 France | Adrian Mannarino | 61 | 8 |
The following players received wildcards into the singles main draw:
The following entrant has been granted a Special Exemption into the main draw:
The following players received entry from the qualifying draw:
See main article: 2011 Delray Beach International Tennis Championships – Singles qualifying.
The following players received entry as a lucky loser into the singles main draw:
See main article: 2011 Delray Beach International Tennis Championships – Singles. 
Juan Martín del Potro defeated Janko Tipsarević, 6–4, 6–4
See main article: 2011 Delray Beach International Tennis Championships – Doubles. 
Scott Lipsky / Rajeev Ram defeated Christopher Kas / 
Alexander Peya, 4–6, 6–4, [10–3]
