The 2011 Barcelona Ladies Open was a tennis tournament played on outdoor clay courts. It was the 5th edition of the Barcelona Ladies Open, and an International-level tournament on the 2011 WTA Tour. It took place at the Tennis de la Vall d'Hebron in Barcelona, Catalonia, Spain, from April 25 through May 1, 2011.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 France | Marion Bartoli | 12 | 1 | |
 Romania | Alexandra Dulgheru | 28 | 2 | |
| Tsvetana Pironkova | 35 | 3 | ||
 Russian Federation | Ekaterina Makarova | 38 | 4 | |
 Italy | Sara Errani | 41 | 5 | |
| Italy | Roberta Vinci | 42 | 6 | |
 Czech Republic | Iveta Benešová | 44 | 7 | |
 Spain | 45 | |||
| Czech Republic | Barbora Záhlavová-Strýcová | 47 | 9 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
See main article: 2011 Barcelona Ladies Open – Singles qualifying.
The following players received entry from a lucky loser spot:
Lourdes Domínguez Lino (foot injury)See main article: 2011 Barcelona Ladies Open – Singles. Roberta Vinci def. Lucie Hradecká, 4–6, 6–2, 6–2
See main article: 2011 Barcelona Ladies Open – Doubles. Iveta Benešová / Barbora Záhlavová-Strýcová def. Natalie Grandin / Vladimíra Uhlířová, 5–7, 6–4, [11–9]
