The 2011 Alessandria Challenger was a professional tennis tournament played on clay courts. It was the fourth edition of the tournament which is part of the 2011 ATP Challenger Tour. It took place in Alessandria, Italy between 23 and 29 May 2011.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Argentina | Diego Junqueira | 105 | 1 | |
 Brazil | João Souza | 128 | 2 | |
 Italy | Paolo Lorenzi | 131 | 3 | |
 Austria | Martin Fischer | 139 | 4 | |
| Paul Capdeville | 141 | 5 | ||
| Brazil | Rogério Dutra da Silva | 142 | 6 | |
| Italy | Alessio di Mauro | 151 | 7 | |
 Slovenia | Grega Žemlja | 156 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry as an alternate into the singles main draw:
The following players received entry as a special exempt into the singles main draw:
The following players received entry from the qualifying draw:
See main article: 2011 Alessandria Challenger – Singles. 
Pablo Carreño Busta def. Roberto Bautista Agut, 3–6, 6–3, 7–5
See main article: 2011 Alessandria Challenger – Doubles. Martin Fischer / Philipp Oswald def. Jeff Coetzee / 
Andreas Siljeström, 6–7(5), 7–5, [10–6]
