The 2011 ATP Challenger Guangzhou was a professional tennis tournament played on hard courts. It was the second edition of the tournament which was part of the 2011 ATP Challenger Tour. It took place in Guangzhou, China between 14 and 20 March 2011.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Japan | Go Soeda | 109 | 1 | |
 Slovakia | Lukáš Lacko | 119 | 2 | |
 Belgium | Steve Darcis | 129 | 3 | |
 Russian Federation | Alexander Kudryavtsev | 144 | 4 | |
| Matthias Bachinger | 160 | 5 | ||
| Japan | Tatsuma Ito | 173 | 6 | |
 Belarus | Uladzimir Ignatik | 200 | 7 | |
| Dominik Meffert | 211 | 8 |
The following players received wildcards into the singles main draw:
The following entrant has been granted a Special Exemption into the main draw:
The following players received entry from the qualifying draw:
See main article: 2011 ATP Challenger Guangzhou – Singles. Uladzimir Ignatik def. Alexander Kudryavtsev, 6–4, 6–4
See main article: 2011 ATP Challenger Guangzhou – Doubles. Mikhail Elgin / Alexander Kudryavtsev def. 
Sanchai Ratiwatana / Sonchat Ratiwatana, 7–6(3), 6–3
