| Competition: | Segunda División |
| Season: | 2011–12 |
| Winners: | Central Español (3rd title) |
| Promoted: | Central Español Juventud Progreso |
| League Topscorer: | Ramón Valencio (18 goals) |
| Biggest Home Win: | (19 May 2012) |
| Biggest Away Win: | (21 December 2011) Huracán 0–4 Miramar Misiones (21 April 2012) |
| Highest Scoring: | (10 December 2011) |
| Matches: | 170 |
| Total Goals: | 424 |
| Longest Wins: | 9 games: Central Español |
| Longest Unbeaten: | 19 games: Central Español |
| Longest Winless: | 12 games: Rocha Villa Teresa |
| Longest Losses: | 5 games: Villa Teresa |
| Prevseason: | 2010–11 |
| Nextseason: | 2012–13 |
The 2011–12 Uruguayan Segunda División is the season of second division professional of football in Uruguay. A total of 13 teams will compete; the top two teams and the winner of the Championship play-offs are promoted to the Uruguayan Primera División.
| Team | Manager1 | Captain | Kit manufacturer | Shirt main sponsor | |
|---|---|---|---|---|---|
| Atenas | Wilmar Cabrera | Gabriel Alcoba | Mass | TV cable 8 digital | |
| Boston River | Fernando Helo | Marcelo De Souza | Matgeor | Buquebus | |
| Central Español | Ronald Ramirez | Matgeor | La Selva | ||
| Deportivo Maldonado | Julio Ribas | Gonzalo Amarilla | Matgeor | Rinde dos | |
| Huracán | Carlos Rodao | Gonzalo Ancheta | Mgr Sport | INOX | |
| Juventud | Ariel De Armas | Pablo Tiscornia | Matgeor | IARA | |
| Miramar Misiones | Carlos Manta | Adrián Berbia | Mgr Sport | Cymaco | |
| Plaza Colonia | Alejandro Villoldo | Matgeor | Rinde dos | ||
| Progreso | Leonardo Ramos | Fabián Canobbio | Matgeor | Rinde dos | |
| Rocha | Fernando Alvez | Leonardo Maldonado | Mgr Sport | Rutas del Sol | |
| Sud América | Alejandro Apud | Fabián Yantorno | Matgeor | Las Acacias | |
| Tacuarembó | Gustavo Ferraz | Walt Báez | Mgr Sport | Agencia Central | |
| Villa Teresa | Vito Beato | Diego Bértola | Mgr Sport | Milwaukee |
Huracán and Progreso qualified to the promotion playoff finals by winning their respectively matches by a single-elimination format, with each tie played over two legs.
Progreso won the match via penalties and became promoted to the 2012–13 Primera División.
| Rank | Player | Nationality | Club | Goals | |
|---|---|---|---|---|---|
| align=center | 1 | Ramón Valencio | Central Español | 18 | |
| align=center | 2 | Sergio Souza | Central Español | 13 | |
| align=center | 3 | Miguel Puglia | Juventud | 12 | |
| align=center rowspan=2 | 4 | Sebastián Fernández | Miramar Misiones | 10 | |
| Santiago Bello | Deportivo Maldonado | 10 |