| Season: | 2011–12 |
| Winners: | Jablonec (group Bratislava) Piešťany (group West) Martin (group Middle) Humenné (group East) |
| Nextseason: | 2012–13 |
The 2011–12 season of Majstrovstvá regiónu was the nineteen season of the fourth-tier football league in Slovakia, since its establishment in 1993.
64 teams were geographically divided into four groups: Majstrovstvá regiónu Bratislava, Majstrovstvá regiónu Západ, Majstrovstvá regiónu Stred and Majstrovstvá regiónu Východ (16 teams each). Teams were played against teams in their own division only.