| Score: | 6–1, 7–5, 7–5 |
| Draw: | 64 (4 / 4) |
| Seeds: | 16 |
See main article: 2010 Wimbledon Championships. Daniel Nestor and Nenad Zimonjić were the two-time defending champions, but lost in the second round to Chris Eaton and Dominic Inglot.
Jürgen Melzer and Philipp Petzschner defeated Robert Lindstedt and Horia Tecău in the final, 6–1, 7–5, 7–5, to win the gentlemen's doubles title at the 2010 Wimbledon Championships.[1]
See also: 1 and 1. 
Daniel Nestor / 
Nenad Zimonjić (second round)
See also: 2 and 4. 
Bob Bryan / Mike Bryan (quarterfinals)
See also: 3 and 3. 
Lukáš Dlouhý / 
Leander Paes (second round)
See also: 4 and 2. Mahesh Bhupathi / 
Max Mirnyi (third round)
See also: 5 and 1. 
Łukasz Kubot / 
Oliver Marach (first round)
See also: 6 and 3. Mariusz Fyrstenberg / Marcin Matkowski (second round)
See also: 7 and 4. Wesley Moodie / 
Dick Norman (semifinals)
See also: 8 and 2. Julian Knowle / 
Andy Ram (third round)
See also: 9 and 4. František Čermák / 
Michal Mertiňák (second round)
See also: 10 and 3. 
Simon Aspelin / 
Paul Hanley (second round)
See also: 11 and 2. 
Marcel Granollers / Tommy Robredo (quarterfinals)
See also: 12. John Isner / Sam Querrey (withdrew)
See also: 13 and 3. Mardy Fish / Mark Knowles (first round)
See also: 14 and 1. 
Julien Benneteau / Michaël Llodra (quarterfinals)
See also: 15 and 4. 
Marcelo Melo / Bruno Soares (second round)
See also: 16 and 2. Robert Lindstedt / Horia Tecău (final)
John Isner and Sam Querrey withdrew due to Isner's fatigue after his first round singles match against Nicolas Mahut.
See main article: 2010 Wimbledon Championships – Men's doubles qualifying.