The 2010 edition of the Vuelta Mexico Telmex was won by Óscar Sevilla of Rock Racing Team.
| Year | Winner | Nationality | Team |
|---|---|---|---|
| Overall Leader | Óscar Sevilla | Rock Racing | |
| Combativity Leader | Florencio Ramos | Chiapas Tequila Afamado | |
| Mountain Leader | Rodolfo Torres | Boyacá Orgullo Nacional | |
| Best Mexican | Ignacio Sarabia | Rock Racing | |
| u23 leader | Jose Ramon Aguirre | Canel's Turbo | |
Amore & Vita Conad
Arenas Tlaxcala
Bocaya Orgullo de América Canel's Turbo
CKT Champion System Empacadora San Marcos ISD Neri Orven PRODEG CEDAJ Guanajuato Rock Racing Selección Chiapas Tequila Afamado
Selección Cuba
Selección Venezuela
Spider Tech by Planet Energy
Team Raleigh
Team Type One Veracruz| Stage | Date | Course | Distance | Type | Winner | ||
|---|---|---|---|---|---|---|---|
| 1 | April 17 | Aldo Ilesic | |||||
| 2 | April 18 | 108 | Medium-mountain stage | François Parisien | |||
| 3 | April 19 | 173 | Ignacio Sarabia | ||||
| 4 | April 20 | 220 |  Luis F. Macías | ||||
| 5 | April 21 | 175 | Flavio de Luna | ||||
| 6 | April 23 | 180 | Mountain stage | Ignacio Sarabia | |||
| 7 | April 24 | 11 | Rodolfo Torres | ||||
| 8 | April 25 | 100 | Flat stage | Philip Nielsen | |||
| Rank | Rider | Team | Time | |
|---|---|---|---|---|
| Rock Racing | 26h 34 18" | |||
| 2 | Boyacá Orgullo de America | + 13" | ||
| 3 | Boyacá Orgullo de America | + 18" | ||
| 4 | Orven | + 45" | ||
| 5 | Rock Racing | + 46" |