See main article: 2010 USTA LA Tennis Open. Harsh Mankad and Frederik Nielsen were the defending champions, but Nielsen chose not to compete this year.
Mankad partnered up with Samuel Groth, but they lost in the semifinals against Brian Battistone and Nicholas Monroe.
Battistone and Monroe won in the final 5–7, 6–3, [10–4] against Artem Sitak and Leonardo Tavares.