| Year: | 2010 |
| Team: | Tulane Green Wave |
| Conference: | Conference USA |
| Short Conf: | CUSA |
| Division: | West |
| Record: | 4–8 |
| Conf Record: | 2–6 |
| Hc Year: | 4th |
| Off Coach: | Dan Dodd |
| Oc Year: | 4th |
| Dc Year: | 2nd |
| Stadium: | Louisiana Superdome |
The 2010 Tulane Green Wave football team represented Tulane University in the 2010 college football season. The Green Wave, led by fourth-year head coach Bob Toledo, are members of Conference USA in the West Division and played their home games at the Louisiana Superdome. They finished the season 4–8, 2–6 in C-USA play.