| Champ: |  Karol Beck |
| Runner: |  Gilles Müller |
| Score: | 6–7(4), 6–4, 7–5 |
| Type: | singles doubles |
See main article: 2010 Tashkent Challenger. Marcos Baghdatis was the defending champion but decided not to participate this year.
Karol Beck won against Gilles Müller 6–7(4), 6–4, 7–5 in the final.